Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801658 | 0.88 | GRIN2B (0.44) | USP30GRIN2BGRIN2C | |
| SCHEMBL30801701 | 0.88 | USP30 (0.40) | USP30GRIN2BGRIN2CGPR119HDAC1 | |
| SCHEMBL30801731 | 0.84 | USP30 (0.38) | USP30GRIN2BGRIN2CGPR119HDAC1 | |
| SCHEMBL27336111 | 0.81 | GRIN2B (0.63) | USP30GRIN2BGRIN2CGPR119HDAC1 | |
| SCHEMBL30801707 | 0.80 | USP30 (0.45) | USP30GPR119HDAC1HDAC8HDAC6 | |
| SCHEMBL19851172 | 0.80 | GRIN2B (0.45) | USP30GRIN2BGRIN2CUSP2SMN1; SMN2 | |
| SCHEMBL19853723 | 0.79 | JAK2 (0.37) | — | |
| SCHEMBL20804212 | 0.77 | GRIN2B (0.70) | GRIN2BGRIN2C | |
| SCHEMBL30801667 | 0.77 | USP30 (0.43) | USP30GRIN2BGRIN2CDDB1CRBN | |
| SCHEMBL17712353 | 0.77 | GRIN2B (0.70) | GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |