Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801690 | 0.91 | USP30 (0.41) | USP30MEN1KMT2AMAPTYAP1 | |
| SCHEMBL24178939 | 0.83 | EPHX2 (0.39) | L3MBTL1 | |
| SCHEMBL19839380 | 0.83 | EPHX2 (0.39) | L3MBTL1 | |
| SCHEMBL27336109 | 0.81 | USP30 (0.45) | USP30MEN1KMT2ATACR1OPRD1 | |
| SCHEMBL19854347 | 0.80 | CSNK1A1 (0.40) | MEN1KMT2ATSHR | |
| SCHEMBL23324435 | 0.79 | USP30 (0.51) | USP30MEN1KMT2ATACR1OPRD1 | |
| SCHEMBL23298094 | 0.79 | USP30 (0.51) | USP30MEN1KMT2ATACR1OPRD1 | |
| SCHEMBL28822016 | 0.79 | USP30 (0.51) | USP30MEN1KMT2ATACR1OPRD1 | |
| SCHEMBL23324436 | 0.79 | USP30 (0.51) | USP30MEN1KMT2ATACR1OPRD1 | |
| SCHEMBL23298091 | 0.79 | USP30 (0.51) | USP30MEN1KMT2ATACR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |