Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 10/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801794 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3ATMROCK2 | |
| SCHEMBL30801832 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3ATMROCK2 | |
| SCHEMBL30801843 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3ATMROCK2 | |
| SCHEMBL23574122 | 0.83 | USP30 (0.38) | ATMROCK2ROCK1CDC42BPBPIK3C3 | |
| SCHEMBL23573962 | 0.83 | USP30 (0.38) | ATMROCK2ROCK1CDC42BPBPIK3C3 | |
| SCHEMBL23573963 | 0.83 | USP30 (0.38) | ATMROCK2ROCK1CDC42BPBPIK3C3 | |
| SCHEMBL23574056 | 0.83 | USP30 (0.38) | ATMROCK2ROCK1CDC42BPBPIK3C3 | |
| SCHEMBL23574045 | 0.83 | USP30 (0.38) | ATMROCK2ROCK1CDC42BPBPIK3C3 | |
| SCHEMBL30801881 | 0.74 | USP30 (0.45) | — | |
| SCHEMBL30801791 | 0.74 | USP30 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |