Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21542144 | 1.00 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL21542147 | 0.90 | MAPT (0.54) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1541487 | 0.85 | MAPT (0.64) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1700469 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL523822 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1811004 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL523824 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1700465 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL31286223 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1700574 | 0.84 | MAPT (0.55) | MAPTPKMPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565815-B1 | COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS | FOCHON PHARMACEUTICALS LTD (CN) | 2024-03-13 | — | — | EP | disclosed |