Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.87 |
| ▸ | AKT2 | P31751 | 14/20 | 0.87 |
| ▸ | AKT3 | Q9Y243 | 13/20 | 0.87 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191503 | 0.93 | AKT1 (1.00) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL25386420 | 0.93 | AKT1 (0.78) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455728 | 0.92 | AKT1 (0.92) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL27385313 | 0.91 | AKT1 (0.79) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455748 | 0.91 | AKT1 (0.92) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455625 | 0.90 | AKT1 (0.91) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455814 | 0.90 | AKT1 (0.82) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL31455754 | 0.89 | AKT1 (0.79) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL25384109 | 0.89 | AKT1 (0.70) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL2191882 | 0.89 | AKT1 (0.75) | AKT1AKT2AKT3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |