Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.62 |
| ▸ | AKT2 | P31751 | 14/20 | 0.61 |
| ▸ | AKT3 | Q9Y243 | 14/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27226383 | 1.00 | AKT1 (0.62) | AKT1AKT2AKT3CYP2C9CYP1A2 | |
| SCHEMBL30802357 | 0.97 | AKT1 (0.58) | AKT1AKT2AKT3CYP2C9CYP1A2 | |
| SCHEMBL27227521 | 0.97 | AKT1 (0.58) | AKT1AKT2AKT3CYP2C9CYP1A2 | |
| SCHEMBL27227329 | 0.94 | AKT1 (0.55) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL27226163 | 0.94 | AKT1 (0.58) | AKT1AKT2AKT3CYP2C9CYP1A2 | |
| SCHEMBL27226413 | 0.94 | AKT1 (0.55) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL27227350 | 0.92 | AKT1 (0.56) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL27227622 | 0.92 | AKT1 (0.51) | AKT1AKT2AKT3CYP2C9 | |
| SCHEMBL27227314 | 0.92 | AKT1 (0.53) | AKT1AKT2AKT3CYP2C9CYP1A2 | |
| SCHEMBL27263140 | 0.92 | AKT1 (0.57) | AKT1AKT2AKT3CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024107565-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |