Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095473 | 1.00 | NR4A2 (0.47) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL4462372 | 0.87 | NR4A2 (0.47) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL16056048 | 0.87 | NR4A2 (0.47) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL275285 | 0.87 | NR4A2 (0.49) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL30752924 | 0.87 | NR4A2 (0.49) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL15100966 | 0.86 | HPGD (0.47) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL3712715 | 0.85 | NR4A2 (0.50) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL16304136 | 0.83 | NR4A2 (0.49) | NR4A2L3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL28819764 | 0.83 | KDM4E (0.49) | NR4A2ALDH1A1CA1CA2HSD17B10 | |
| SCHEMBL28068823 | 0.83 | ABL1 (0.55) | NR4A2L3MBTL1ALDH1A1LMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561244-A | Isoindolinone compounds and uses thereof | 杭州格博生物医药有限公司 | 2024-02-13 | — | — | CN | disclosed |