Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 1.00 |
| ▸ | ABL1 | P00519 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | KDR | P35968 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | FABP6 | P51161 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455699 | 0.84 | ABL1 (0.77) | XIAPABL1ALDH1A1KDRLMNA | |
| Mebendazole SCHEMBL536464 | 0.82 | ABL1 (1.00) | XIAPABL1ALDH1A1KDRLMNA | |
| Mebendazole SCHEMBL29390263 | 0.82 | ABL1 (1.00) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL14643226 | 0.81 | XIAP (0.68) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL14643048 | 0.80 | ABL1 (1.00) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL14643024 | 0.79 | XIAP (0.64) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL24209313 | 0.78 | ABL1 (0.79) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL14643027 | 0.77 | ABL1 (0.89) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL12420287 | 0.77 | ABL1 (0.66) | XIAPABL1ALDH1A1KDRLMNA | |
| SCHEMBL14643046 | 0.77 | ABL1 (1.00) | XIAPABL1ALDH1A1KDRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083846-A1 | SMAC MIMETICS FOR TREATMENT OF CANCER, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-03-14 | — | — | US | claimed |
| US-20240083846-A1 | SMAC MIMETICS FOR TREATMENT OF CANCER, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2024-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083846-A1 | SMAC MIMETICS FOR TREATMENT OF CANCER, PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION THEREOF | BIRC5, BIRC2, BIRC3 | XIAP 6/4885ABL1 3292/4885ALDH1A1 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.