Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26023158 | 0.87 | OPRL1 (0.47) | OPRL1EGLN1OPRM1OPRK1 | |
| SCHEMBL18181139 | 0.84 | EGLN1 (0.39) | OPRL1EGLN1OPRM1OPRK1 | |
| SCHEMBL30683634 | 0.77 | EGLN1 (0.37) | OPRL1EGLN1 | |
| SCHEMBL15690620 | 0.77 | CALCRL (0.40) | OPRL1EGLN1 | |
| SCHEMBL31436564 | 0.77 | KCNK2 (0.36) | OPRL1 | |
| SCHEMBL21904215 | 0.77 | CALCRL (0.34) | OPRL1EGLN1OPRM1 | |
| SCHEMBL17506425 | 0.77 | EGLN1 (0.36) | OPRL1EGLN1 | |
| SCHEMBL21904530 | 0.76 | CPT1A (0.36) | OPRL1 | |
| SCHEMBL16618821 | 0.75 | CNR1 (0.54) | OPRL1EGLN1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL25316481 | 0.75 | OPRL1 (0.36) | OPRL1EGLN1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4583977-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052512-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-14 | — | — | WO | disclosed |