Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.70 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.70 |
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 3/20 | 0.47 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729513 | 0.90 | CRBN (0.69) | CRBNDDB1HPGDSARGSPT1 | |
| SCHEMBL30741714 | 0.90 | CRBN (0.69) | CRBNDDB1HPGDSARGSPT1 | |
| SCHEMBL30741730 | 0.88 | CRBN (0.68) | CRBNDDB1HPGDSAR | |
| SCHEMBL22291243 | 0.88 | CRBN (0.68) | CRBNDDB1HPGDSAR | |
| SCHEMBL27064359 | 0.88 | CRBN (0.65) | CRBNDDB1HPGDSARGSPT1 | |
| SCHEMBL31173698 | 0.86 | CRBN (0.66) | CRBNDDB1HPGDSAR | |
| SCHEMBL30741747 | 0.86 | CRBN (0.66) | CRBNDDB1HPGDSAR | |
| SCHEMBL29927280 | 0.85 | CRBN (0.67) | CRBNDDB1HPGDSAR | |
| SCHEMBL23754672 | 0.85 | CRBN (0.67) | CRBNDDB1HPGDSAR | |
| SCHEMBL23173195 | 0.85 | CRBN (0.64) | CRBNDDB1HPGDSAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054625-A2 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |