Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829387 | 1.00 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30972502 | 0.90 | HDAC2 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18112961 | 0.83 | HTT (0.46) | TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19990164 | 0.82 | HTT (0.46) | LMNATSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL19990163 | 0.82 | HTT (0.46) | LMNATSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30805753 | 0.81 | HDAC8 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29828847 | 0.81 | HDAC8 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28984824 | 0.81 | CYP1A2 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30805768 | 0.81 | CYP1A2 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL29828392 | 0.81 | CYP1A2 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805108-B | Preparation method of chiral beta-alkylamide compound | 南方科技大学 | 2023-12-26 | — | — | CN | disclosed |