Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.55 |
| ▸ | JAK3 | P52333 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30807324 | 1.00 | BTK (0.55) | BTKJAK3MAP4K4HPGDPDE10A | |
| SCHEMBL973857 | 0.93 | HPGD (0.50) | BTKJAK3MAP4K4HPGDPDE10A | |
| SCHEMBL972766 | 0.88 | HPGD (0.45) | BTKJAK3MAP4K4HPGDPDE10A | |
| SCHEMBL4892745 | 0.86 | HPGD (0.58) | HPGDPDE10ACTSK | |
| SCHEMBL30807226 | 0.82 | HPGD (0.48) | BTKJAK3MAP4K4HPGDLCK | |
| SCHEMBL28138963 | 0.81 | BTK (0.57) | BTKJAK3MAP4K4HPGDPDE10A | |
| SCHEMBL28138962 | 0.81 | BTK (0.57) | BTKJAK3MAP4K4HPGDPDE10A | |
| SCHEMBL25520140 | 0.80 | DPP4 (0.44) | BTKHPGDDPP4 | |
| SCHEMBL30807237 | 0.80 | BTK (0.51) | BTKJAK3MAP4K4PDE10ACA1 | |
| SCHEMBL27142655 | 0.80 | BTK (0.51) | BTKJAK3MAP4K4PDE10ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577211-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | Wake Forest University Health Sciences (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |