Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 9/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25637211 | 1.00 | LIMK1 (0.41) | LIMK1PDPK1HTTSMN1; SMN2PRKCI | |
| SCHEMBL21880616 | 0.81 | CDK1 (0.35) | PDPK1HTTSMN1; SMN2PRKCIPIK3CA | |
| SCHEMBL13780028 | 0.79 | PDPK1 (0.39) | PDPK1SMN1; SMN2PRKCIPIK3CANPSR1 | |
| SCHEMBL5313472 | 0.78 | PDPK1 (0.38) | PDPK1HTTSMN1; SMN2PRKCIPIK3CA | |
| SCHEMBL12094370 | 0.76 | PDPK1 (0.37) | PDPK1SMN1; SMN2PRKCIPIK3CANPSR1 | |
| SCHEMBL5579149 | 0.76 | PDPK1 (0.37) | PDPK1SMN1; SMN2PRKCIPIK3CANPSR1 | |
| SCHEMBL19933209 | 0.73 | PRKCI (0.40) | PDPK1HTTSMN1; SMN2PRKCINPSR1 | |
| SCHEMBL25171225 | 0.72 | PDPK1 (0.37) | PDPK1SMN1; SMN2PRKCIPIK3CANOS1 | |
| SCHEMBL20777126 | 0.72 | PIK3CA (0.38) | PDPK1HTTSMN1; SMN2PRKCIPIK3CA | |
| SCHEMBL1868539 | 0.72 | NPC1 (0.50) | LIMK1PDPK1MAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |