Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915211 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL31536518 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL26915206 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL30809500 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL26915164 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL31725079 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL26915155 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL30884801 | 0.78 | KDM4E (0.81) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL21450560 | 0.78 | KDM4E (0.81) | KDM4EALDH1A1HSD17B10ALOX15MEN1 | |
| SCHEMBL21593903 | 0.78 | MAPT (0.56) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567478-A | Camptothecins compound and its preparation method and application | 四川科伦博泰生物医药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |