SCHEMBL30809552

SCHEMBL30809552

CC(O)(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
EPHX2 P34913 1/20 0.50
CASP3 P42574 2/20 0.47
FABP5 Q01469 3/20 0.46
FABP7 O15540 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6647665 1.00 KMT2A (0.53) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL119779 0.88 KMT2A (0.54) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL29362505 0.88 KMT2A (0.54) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL29503775 0.88 KMT2A (0.54) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL6673476 0.88 KMT2A (0.54) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL10205819 0.86 KMT2A (0.58) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL1880388 0.85 KMT2A (0.55) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL12560390 0.85 KMT2A (0.52) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL8687186 0.85 KMT2A (0.52) KMT2AMDM4TP53EPHX2CASP3
SCHEMBL25178730 0.84 KMT2A (0.51) KMT2AMDM4TP53EPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567478-A Camptothecins compound and its preparation method and application 四川科伦博泰生物医药股份有限公司 2024-02-20 CN disclosed