Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19126567 | 1.00 | KDR (0.46) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL19126329 | 0.95 | KDR (0.44) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL19126472 | 0.92 | KDR (0.45) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL19126526 | 0.91 | KDR (0.43) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL30810595 | 0.91 | KDR (0.43) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL30810572 | 0.91 | KDR (0.43) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL19126459 | 0.91 | KDR (0.43) | KDRFLT3NAMPTGPR183KMT2A | |
| SCHEMBL30810509 | 0.90 | GPR183 (0.45) | KDRGPR183PIK3CAMGLLHRH4 | |
| SCHEMBL19126369 | 0.90 | GPR183 (0.45) | KDRGPR183PIK3CAMGLLHRH4 | |
| SCHEMBL19126392 | 0.90 | KDR (0.46) | KDRFLT3KMT2AMAPK14PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939314-B2 | Quinolin-2-one derivatives | MERCK PATENT GMBH (DE) | 2024-03-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939314-B2 | Quinolin-2-one derivatives | KIT, CDK2, CDK1 | KDR 792/4885FLT3 5/4885NAMPT 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.