Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30812218 | 0.88 | BRD4 (0.43) | BRD4BRD2BRD3BRDT | |
| SCHEMBL30824804 | 0.85 | BRD4 (0.41) | BRD4HDAC1HDAC6 | |
| SCHEMBL30811953 | 0.85 | BRD4 (0.49) | BRD4HDAC1HDAC6BRD2BRD3 | |
| SCHEMBL30812104 | 0.82 | BRD4 (0.46) | BRD4BRD2BRD3BRDT | |
| SCHEMBL30812303 | 0.82 | BRD4 (0.45) | BRD4HDAC1HDAC6 | |
| SCHEMBL30812063 | 0.81 | BRD4 (0.46) | BRD4 | |
| SCHEMBL30812009 | 0.81 | BRD4 (0.48) | BRD4 | |
| SCHEMBL30812005 | 0.81 | BRD4 (0.47) | BRD4 | |
| SCHEMBL30812145 | 0.81 | BRD4 (0.47) | BRD4BRD2BRD3BRDT | |
| SCHEMBL31683654 | 0.80 | BRD4 (0.49) | BRD4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |