Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 15/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824772 | 0.84 | UTS2R (0.34) | IKBKBCHUKUTS2RTBK1HTR1A | |
| SCHEMBL27393380 | 0.84 | UTS2R (0.34) | IKBKBCHUKUTS2RTBK1HTR1A | |
| SCHEMBL30812305 | 0.84 | IKBKB (0.34) | IKBKBCHUKUTS2RTBK1HTR1A | |
| SCHEMBL30824826 | 0.79 | UTS2R (0.34) | IKBKBCHUKUTS2RTBK1HTR1A | |
| SCHEMBL27391581 | 0.79 | UTS2R (0.34) | IKBKBCHUKUTS2RTBK1HTR1A | |
| SCHEMBL21851287 | 0.76 | NPY1R (0.35) | TBK1SLC6A4 | |
| SCHEMBL30812308 | 0.76 | NPY1R (0.35) | IKBKBTBK1 | |
| SCHEMBL31246021 | 0.73 | UTS2R (0.35) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL30812175 | 0.73 | UTS2R (0.35) | UTS2RHTR1ACYP2D6DRD2HTR1D | |
| SCHEMBL30812266 | 0.73 | IKBKB (0.41) | IKBKBCHUKUTS2RTBK1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054956-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |