SCHEMBL30812238

SCHEMBL30812238

Cn1cc(-c2cc(C(C)(C)O)ccc2-n2cc(N3CC(CC4CCNCC4)C3)ccc2=O)c2cc[nH]c2c1=O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BRD9 Q9H8M2 7/20 0.45
▸ BRD4 O60885 15/20 0.39
▸ GABBR2 O75899 1/20 0.38
▸ BRD2 P25440 1/20 0.38
▸ EP300 Q09472 1/20 0.38
▸ BRD3 Q15059 1/20 0.38
▸ BRDT Q58F21 1/20 0.38
▸ PBRM1 Q86U86 1/20 0.38
▸ CREBBP Q92793 1/20 0.38
▸ KAT2A Q92830 1/20 0.38
▸ BRD7 Q9NPI1 1/20 0.38
▸ GABBR1 Q9UBS5 1/20 0.38
▸ TAF1 P21675 1/20 0.36
▸ CECR2 Q9BXF3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683453 0.84 BRD4 (0.48) BRD9BRD4
SCHEMBL30811982 0.82 BRD9 (0.46) BRD9BRD4GABBR2BRD2EP300
SCHEMBL30812189 0.81 BRD4 (0.44) BRD9BRD4
SCHEMBL30824882 0.81 BRD9 (0.50) BRD9BRD4GABBR2BRD2EP300
SCHEMBL27393452 0.81 BRD9 (0.50) BRD9BRD4GABBR2BRD2EP300
SCHEMBL30812046 0.81 BRD4 (0.36) BRD4
SCHEMBL30812047 0.80 BRD4 (0.48) BRD9BRD4
SCHEMBL30811961 0.79 EP300 (0.31) EP300
SCHEMBL30812178 0.78 BRD4 (0.45) BRD9BRD4
SCHEMBL30812004 0.77 BRD4 (0.45) BRD9BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2025-12-25 — — US disclosed
WO-2024054956-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388605-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE BRD4, BRDT, BICRA BRD9 10/4885BRD4 1/4885GABBR2 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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