Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 4/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 9/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619934 | 1.00 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL29162317 | 1.00 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619711 | 0.92 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619854 | 0.89 | KCNJ6 (0.39) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619941 | 0.85 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619784 | 0.84 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619946 | 0.84 | P2RX4 (0.42) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619766 | 0.83 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619998 | 0.83 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA | |
| SCHEMBL23619937 | 0.83 | KCNJ5 (0.48) | KCNJ5KCNJ3KCNJ6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901642-B | Fused ring compound and application thereof | 武汉朗来科技发展有限公司 | 2024-02-23 | — | — | CN | disclosed |