SCHEMBL30812872

SCHEMBL30812872

COc1ccc(Nc2ccc3c(S(N)(=O)=O)cc(NC(=O)Cc4ccccc4Cl)cc3n2)cc1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 19/20 0.57
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23619751 1.00 P2RX4 (0.57) P2RX4MAPT
SCHEMBL23619950 0.87 P2RX4 (0.58) P2RX4
SCHEMBL30812805 0.87 P2RX4 (0.58) P2RX4
SCHEMBL23619749 0.86 P2RX4 (0.44) P2RX4MAPT
SCHEMBL23619693 0.86 P2RX4 (0.56) P2RX4
SCHEMBL30812876 0.86 P2RX4 (0.56) P2RX4
SCHEMBL23620101 0.86 MAPT (0.48) P2RX4MAPT
SCHEMBL30812826 0.85 P2RX4 (0.56) P2RX4
SCHEMBL23619777 0.85 P2RX4 (0.56) P2RX4
SCHEMBL24713272 0.84 P2RX4 (0.52) P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901642-B Fused ring compound and application thereof 武汉朗来科技发展有限公司 2024-02-23 CN disclosed