Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.46 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619877 | 1.00 | NR1I2 (0.52) | NR1I2KCNJ5KCNJ3ANO1MAPT | |
| SCHEMBL23619942 | 0.88 | KCNJ5 (0.49) | NR1I2KCNJ5KCNJ3ANO1MAPT | |
| SCHEMBL23619948 | 0.88 | KCNJ5 (0.49) | NR1I2KCNJ5KCNJ3ANO1MAPT | |
| SCHEMBL25144105 | 0.85 | NR1I2 (0.48) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL23619776 | 0.82 | NR1I2 (0.46) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL30812897 | 0.81 | KCNJ5 (0.51) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL23619723 | 0.81 | KCNJ5 (0.51) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL24713227 | 0.78 | KCNJ5 (0.48) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL23619940 | 0.78 | P2RX4 (0.52) | NR1I2KCNJ5KCNJ3ANO1P2RX4 | |
| SCHEMBL30812834 | 0.78 | P2RX4 (0.52) | NR1I2KCNJ5KCNJ3ANO1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901642-B | Fused ring compound and application thereof | 武汉朗来科技发展有限公司 | 2024-02-23 | — | — | CN | disclosed |