Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | AGXT | P21549 | 2/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (S)-M-Methoxyamphetamine SCHEMBL269071 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4IDO1AGXTPNMT | |
| (S)-M-Methoxyamphetamine SCHEMBL3293027 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4IDO1AGXTPNMT | |
| (S)-M-Methoxyamphetamine SCHEMBL11461072 | 1.00 | TAAR1 (1.00) | TAAR1SLC6A4IDO1AGXTPNMT | |
| (S)-M-Methoxyamphetamine SCHEMBL30559562 | 0.98 | TAAR1 (0.96) | TAAR1SLC6A4IDO1AGXTPNMT | |
| (S)-M-Methoxyamphetamine SCHEMBL31545212 | 0.87 | TAAR1 (0.77) | TAAR1SLC6A4IDO1AGXTPNMT | |
| SCHEMBL449889 | 0.86 | TAAR1 (0.76) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL151945 | 0.85 | TAAR1 (0.74) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL8747069 | 0.85 | TAAR1 (0.74) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL6224557 | 0.85 | TAAR1 (0.73) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL13349231 | 0.84 | TAAR1 (0.72) | TAAR1SLC6A4IDO1AGXTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715632-A | Compositions comprising an enzyme-cleavable prodrug and nafamostat and methods of use thereof | 恩赛斯生物科学股份有限公司 | 2024-03-15 | — | — | CN | disclosed |