Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 20/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 18/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20213038 | 1.00 | OPRL1 (0.71) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20213039 | 1.00 | OPRL1 (0.71) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20213221 | 0.92 | OPRL1 (0.66) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20213224 | 0.92 | OPRL1 (0.66) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL30813307 | 0.92 | OPRL1 (0.66) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20213142 | 0.88 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20213143 | 0.88 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL30813258 | 0.88 | OPRL1 (0.68) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL20212821 | 0.86 | OPRL1 (0.74) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL21179570 | 0.86 | OPRL1 (0.74) | OPRL1OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4455145-A2 | PIPERIDINYL NOCICEPTIN RECEPTOR COMPOUNDS | Astraea Therapeutics, LLC (US) | 2024-10-30 | — | — | EP | disclosed |
| US-RE49825-E1 | Piperidinyl nociceptin receptor compounds | ASTRAEA THERAPEUTICS, LLC (US) | 2024-02-06 | — | — | US | disclosed |