Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | ABL2 | P42684 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218035 | 1.00 | SRC (0.44) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL21221307 | 0.92 | USP30 (0.39) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL30813401 | 0.91 | USP30 (0.38) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL30813501 | 0.89 | USP30 (0.36) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL30813511 | 0.88 | SRC (0.39) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL30813509 | 0.87 | USP30 (0.39) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL27217761 | 0.86 | USP30 (0.36) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL27217808 | 0.85 | SRC (0.35) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL27218001 | 0.85 | SRC (0.39) | SRCEGFRABL1ABL2USP30 | |
| SCHEMBL27217649 | 0.83 | USP30 (0.38) | SRCEGFRUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |