Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 5/20 | 0.41 |
| ▸ | SRC | P12931 | 11/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KIF5B | P33176 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217886 | 0.89 | SRC (0.41) | RIPK2SRCEGFRRETKIF5B | |
| SCHEMBL27217844 | 0.86 | SRC (0.40) | RIPK2SRCEGFR | |
| SCHEMBL30813564 | 0.85 | SRC (0.41) | RIPK2SRCEGFRRETKIF5B | |
| SCHEMBL27217745 | 0.82 | SRC (0.38) | SRCEGFR | |
| SCHEMBL30813574 | 0.82 | SRC (0.40) | RIPK2SRCEGFR | |
| SCHEMBL27217970 | 0.82 | SRC (0.40) | RIPK2SRCEGFR | |
| SCHEMBL27217994 | 0.81 | SRC (0.44) | SRCEGFR | |
| SCHEMBL27217748 | 0.80 | SRC (0.46) | RIPK2SRCEGFR | |
| SCHEMBL30813442 | 0.79 | SRC (0.49) | SRCEGFR | |
| SCHEMBL27217705 | 0.79 | SRC (0.49) | SRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |