Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217956 | 1.00 | SRC (0.45) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL27217619 | 0.86 | SRC (0.49) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL30813369 | 0.86 | SRC (0.49) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL27217966 | 0.81 | CYP1A2 (0.38) | MAPTCYP3A4KMT2AMEN1CYP2C9 | |
| SCHEMBL30813701 | 0.81 | CYP1A2 (0.38) | MAPTCYP3A4KMT2AMEN1CYP2C9 | |
| SCHEMBL30813537 | 0.80 | SRC (0.48) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL27217722 | 0.80 | SRC (0.48) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL30813419 | 0.79 | EPHX2 (0.44) | SRCEGFRABL1ABL2EPHX2 | |
| SCHEMBL30813518 | 0.78 | CYP1A2 (0.45) | MAPTCYP3A4KMT2AMEN1CYP2C9 | |
| SCHEMBL27217755 | 0.78 | CYP1A2 (0.45) | MAPTCYP3A4KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |