Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217891 | 1.00 | USP30 (0.38) | USP30BACE1BACE2AAK1 | |
| SCHEMBL30813409 | 0.91 | USP30 (0.39) | USP30BACE1BACE2AAK1 | |
| SCHEMBL29998475 | 0.87 | USP30 (0.39) | USP30BACE1BACE2AAK1 | |
| SCHEMBL27217794 | 0.86 | USP30 (0.37) | USP30BACE1BACE2 | |
| SCHEMBL27088108 | 0.83 | USP30 (0.37) | USP30BACE1BACE2 | |
| SCHEMBL30813487 | 0.81 | USP30 (0.44) | USP30BACE1BACE2AAK1 | |
| SCHEMBL27218030 | 0.81 | PDPK1 (0.33) | — | |
| SCHEMBL30813659 | 0.81 | PDPK1 (0.33) | — | |
| SCHEMBL21221307 | 0.80 | USP30 (0.39) | USP30BACE1BACE2 | |
| SCHEMBL30813573 | 0.78 | USP30 (0.38) | USP30BACE1BACE2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |