Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK7 | Q8TDX7 | 12/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27217896 | 1.00 | NEK7 (0.47) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL30813341 | 0.94 | NEK7 (0.47) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL27217873 | 0.94 | NEK7 (0.47) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL27217954 | 0.93 | NEK7 (0.45) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL30813609 | 0.93 | NEK7 (0.45) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL27217963 | 0.92 | NEK7 (0.55) | NEK7BRAF | |
| SCHEMBL30813624 | 0.91 | BRAF (0.41) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL27217883 | 0.91 | BRAF (0.41) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL27217639 | 0.89 | NEK7 (0.44) | NEK7BRAFKDRKITKCNH2 | |
| SCHEMBL30813528 | 0.88 | BRAF (0.40) | NEK7BRAFKDRKITKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |