Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703327 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| SCHEMBL20859027 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| SCHEMBL20853469 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| SCHEMBL30814176 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| SCHEMBL16703831 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| SCHEMBL16703830 | 1.00 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| Hydrochloric Acid SCHEMBL20731105 | 0.99 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| Hydrochloric Acid SCHEMBL16702881 | 0.99 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| Hydrochloric Acid SCHEMBL18094983 | 0.99 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 | |
| Hydrochloric Acid SCHEMBL30814220 | 0.99 | ELANE (0.48) | ELANEDPP4OPRM1OPRD1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12516023-B2 | NMDA antagonist prodrugs | ASTRAZENECA AB (SE) | 2026-01-06 | — | — | US | claimed |
| CN-111187202-B | NMDA antagonist prodrugs | 阿斯利康(瑞典)有限公司 | 2025-01-21 | — | — | CN | claimed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| CN-111187202-B | NMDA antagonist prodrugs | 阿斯利康(瑞典)有限公司 | 2025-01-21 | — | — | CN | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |