Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MALT1 | Q9UDY8 | 13/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20265650 | 1.00 | POLB (0.64) | POLBMAPTSMN1; SMN2MALT1KDM4E | |
| SCHEMBL20265617 | 0.89 | MALT1 (0.60) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20278408 | 0.88 | MALT1 (0.62) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20278208 | 0.88 | MALT1 (0.60) | POLBMAPTSMN1; SMN2MALT1KDM4E | |
| SCHEMBL20265464 | 0.87 | POLB (0.61) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20265337 | 0.86 | POLB (0.59) | POLBMAPTSMN1; SMN2MALT1KDM4E | |
| SCHEMBL30546555 | 0.84 | MALT1 (0.66) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20265580 | 0.84 | MALT1 (0.66) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20283678 | 0.83 | POLB (0.55) | POLBMAPTSMN1; SMN2MALT1KDM4E | |
| SCHEMBL24802622 | 0.82 | MAPT (0.69) | POLBMAPTSMN1; SMN2MALT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500805-A | Novel urea derivative compounds as RON inhibitors | 株式会社LG化学 | 2024-02-02 | — | — | CN | disclosed |