Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30814368 | 0.83 | BRD4 (0.39) | SMN1; SMN2ALDH1A1NPSR1ATMCYP1A2 | |
| SCHEMBL30814602 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPSR1ATMCYP1A2 | |
| SCHEMBL30814351 | 0.79 | BRD4 (0.41) | SMN1; SMN2ALDH1A1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL24574617 | 0.71 | STING1 (0.36) | SMN1; SMN2ALDH1A1NPSR1PPARGMAPK10 | |
| SCHEMBL28767911 | 0.71 | CYP1A2 (0.44) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL28767901 | 0.70 | STING1 (0.36) | SMN1; SMN2ALDH1A1NPSR1PPARGMAPK10 | |
| SCHEMBL30814557 | 0.70 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1NPSR1ATMCYP1A2 | |
| SCHEMBL30814669 | 0.70 | TSHR (0.38) | SMN1; SMN2ALDH1A1NPSR1CYP1A2CYP2C9 | |
| SCHEMBL926925 | 0.69 | POLB (0.47) | SMN1; SMN2ALDH1A1NPSR1ATMGAA | |
| SCHEMBL925293 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1NPSR1ATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046221-A1 | EGFR INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-03-07 | — | — | WO | disclosed |