Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27226284 | 1.00 | CA1 (0.61) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL17815582 | 0.85 | PRMT1 (0.73) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL1292932 | 0.84 | CA1 (0.65) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL17815580 | 0.82 | CA1 (0.64) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL20422454 | 0.81 | EGFR (0.41) | CA1CA2CA7CA13MAPT | |
| SCHEMBL18413146 | 0.81 | EGFR (0.41) | CA1CA2CA7CA13MAPT | |
| SCHEMBL27227469 | 0.79 | CA1 (0.57) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL4927860 | 0.79 | CA1 (0.69) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL27226032 | 0.79 | CA1 (0.65) | CA1CA2CA7CA13PRMT1 | |
| SCHEMBL1254095 | 0.79 | CA1 (0.77) | CA1CA2CA7CA13PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |