SCHEMBL30815441

SCHEMBL30815441

CC(=O)OCc1ccc(-n2c(-c3cccnc3N)nc3ccc(Br)cc32)cc1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 20/20 0.51
AKT2 P31751 14/20 0.48
AKT3 Q9Y243 9/20 0.47
CYP2C9 P11712 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27226074 1.00 AKT1 (0.51) AKT1AKT2AKT3CYP2C9
SCHEMBL27227556 0.88 AKT1 (0.57) AKT1AKT2AKT3
SCHEMBL30815252 0.88 AKT1 (0.57) AKT1AKT2AKT3
SCHEMBL27226369 0.87 AKT1 (0.49) AKT1AKT2AKT3CYP2C9
SCHEMBL30815861 0.87 AKT1 (0.49) AKT1AKT2AKT3CYP2C9
SCHEMBL27227394 0.83 AKT1 (0.49) AKT1AKT2AKT3CYP2C9
SCHEMBL30815095 0.83 AKT1 (0.49) AKT1AKT2AKT3CYP2C9
SCHEMBL27226064 0.83 AKT1 (0.51) AKT1AKT2AKT3CYP2C9
SCHEMBL30815525 0.82 AKT1 (0.48) AKT1AKT2AKT3CYP2C9
SCHEMBL27226618 0.82 AKT1 (0.48) AKT1AKT2AKT3CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594318-A1 AKT1 MODULATORS Alterome Therapeutics, Inc. (US) 2025-08-06 EP disclosed
WO-2024073371-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed