SCHEMBL30815481

SCHEMBL30815481

CC(C)(C)c1ccc2nc(-c3cccnc3N)n(-c3ccc(CCl)cc3)c2n1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 20/20 0.62
AKT2 P31751 13/20 0.62
AKT3 Q9Y243 9/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27226200 1.00 AKT1 (0.62) AKT1AKT2AKT3
SCHEMBL27227224 0.91 AKT1 (0.62) AKT1AKT2AKT3
SCHEMBL30815359 0.90 AKT1 (0.62) AKT1AKT2AKT3
SCHEMBL27226680 0.90 AKT1 (0.62) AKT1AKT2AKT3
SCHEMBL27307804 0.86 AKT1 (0.71) AKT1AKT2AKT3
SCHEMBL27227328 0.85 AKT1 (0.84) AKT1AKT2AKT3
SCHEMBL30815265 0.85 AKT1 (0.84) AKT1AKT2AKT3
SCHEMBL27226918 0.85 AKT1 (0.80) AKT1AKT2AKT3
SCHEMBL30815642 0.85 AKT1 (0.80) AKT1AKT2AKT3
SCHEMBL30815017 0.84 AKT1 (0.63) AKT1AKT2AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594318-A1 AKT1 MODULATORS Alterome Therapeutics, Inc. (US) 2025-08-06 EP disclosed
WO-2024073371-A1 AKT1 MODULATORS ALTEROME THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed