Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27226295 | 1.00 | TDP1 (0.51) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL27227037 | 0.85 | TDP1 (0.51) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL27227100 | 0.83 | MAPT (0.49) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL13506718 | 0.82 | GSK3B (0.56) | TDP1MAPTMAPK1POLBALDH1A1 | |
| SCHEMBL30815932 | 0.81 | MAPT (0.56) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL27227011 | 0.81 | MAPT (0.56) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL30815754 | 0.81 | TDP1 (0.51) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL27226893 | 0.81 | TDP1 (0.51) | TDP1MAPTMAPK1POLBRAB9A | |
| SCHEMBL30826715 | 0.77 | MAPT (0.64) | TDP1MAPTMAPK1RAB9AALDH1A1 | |
| SCHEMBL12970394 | 0.77 | MAPT (0.64) | TDP1MAPTMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594318-A1 | AKT1 MODULATORS | Alterome Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073371-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |