⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182774 | 0.82 | — | — | |
| SCHEMBL29256069 | 0.72 | — | — | |
| SCHEMBL8831837 | 0.65 | — | — | |
| SCHEMBL176393 | 0.65 | — | — | |
| Pyrazole SCHEMBL18074261 | 0.64 | — | — | |
| SCHEMBL4982271 | 0.64 | — | — | |
| Pyrazole SCHEMBL27665094 | 0.62 | — | — | |
| Pyrazole SCHEMBL27796142 | 0.62 | — | — | |
| Pyrazole SCHEMBL28037467 | 0.62 | — | — | |
| Pyrazole SCHEMBL5664483 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | disclosed |
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | disclosed |
| US-7795294-B2 | Tetrahydro-2H-indazole pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-09-14 | — | — | US | disclosed |
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058313-A1 | TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-03-06 | — | — | US | disclosed |
| WO-2007095513-A1 | TETRAHYDR0-2H-INDAZ0LE DERIVATIVES FOR USE AS CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, NV (BE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007095513-A1 | TETRAHYDR0-2H-INDAZ0LE DERIVATIVES FOR USE AS CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, NV (BE) | 2007-08-23 | — | — | WO | disclosed |