Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24206573 | 0.94 | CRBN (0.55) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL24207321 | 0.94 | CRBN (0.55) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL24207199 | 0.91 | CRBN (0.60) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24754171 | 0.82 | CRBN (0.66) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL24206598 | 0.82 | CRBN (0.54) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL24207005 | 0.81 | CRBN (0.52) | CRBNDDB1POLBGSPT1LMNA | |
| SCHEMBL31171254 | 0.81 | CRBN (0.76) | CRBNDDB1POLBLMNAMAPT | |
| SCHEMBL31171290 | 0.80 | CRBN (0.74) | CRBNDDB1POLBLMNAMAPT | |
| SCHEMBL30817323 | 0.80 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL29021259 | 0.78 | CRBN (0.62) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059808-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |