Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817400 | 0.87 | CRBN (0.48) | CRBNDDB1 | |
| SCHEMBL27293173 | 0.86 | CRBN (0.52) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL30817346 | 0.82 | CRBN (0.48) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25217869 | 0.78 | CRBN (0.64) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31382367 | 0.77 | CRBN (0.47) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL31111977 | 0.77 | CRBN (0.44) | CRBNDDB1POLB | |
| SCHEMBL31111457 | 0.77 | CRBN (0.44) | CRBNDDB1POLB | |
| SCHEMBL26641358 | 0.76 | CRBN (0.64) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25026494 | 0.76 | CRBN (0.54) | CRBNDDB1POLBGSPT1 | |
| SCHEMBL25831464 | 0.74 | CRBN (0.57) | CRBNDDB1POLBGSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059808-A1 | WEE1 INHIBITORS AND METHODS FOR TREATING CANCER | RECURIUM IP HOLDINGS, LLC (US) | 2024-03-21 | — | — | WO | disclosed |