Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 1.00 |
| ▸ | TYRO3 | Q06418 | 2/20 | 1.00 |
| ▸ | JAK2 | O60674 | 14/20 | 0.74 |
| ▸ | JAK1 | P23458 | 13/20 | 0.74 |
| ▸ | JAK3 | P52333 | 3/20 | 0.67 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.67 |
| ▸ | PAK4 | O96013 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.67 |
| ▸ | RET | P07949 | 2/20 | 0.67 |
| ▸ | LTK | P29376 | 2/20 | 0.67 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.67 |
| ▸ | CLK2 | P49760 | 2/20 | 0.67 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.67 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.67 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.67 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.67 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860531 | 1.00 | AXL (1.00) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL15653497 | 1.00 | AXL (1.00) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL15652975 | 1.00 | AXL (1.00) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL29379941 | 1.00 | AXL (1.00) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL30008920 | 1.00 | AXL (1.00) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL860564 | 0.92 | AXL (0.84) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL859327 | 0.89 | AXL (0.81) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL859535 | 0.89 | AXL (0.80) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL13058316 | 0.89 | AXL (0.80) | AXLTYRO3JAK2JAK1JAK3 | |
| SCHEMBL3765087 | 0.89 | AXL (0.80) | AXLTYRO3JAK2JAK1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120053645-A | Dosing regimen for treating PI 3K-related disorders | 因赛特公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119258070-A | Dosing regimen for treating PI 3K-related disorders | 因赛特公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-117800973-A | Salts of PI3K inhibitors and methods of making the same | 因赛特控股公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117777139-A | Salts of PI3K inhibitors and methods of making the same | 因赛特控股公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117736209-A | Salts of PI3K inhibitors and methods of making the same | 因赛特控股公司 | 2024-03-22 | — | — | CN | disclosed |