Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 11/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27241639 | 1.00 | IKZF2 (0.47) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30819859 | 1.00 | IKZF2 (0.47) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30819811 | 0.86 | IKZF2 (0.61) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL27241579 | 0.86 | IKZF2 (0.61) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL20234882 | 0.84 | CRBN (0.55) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL29927677 | 0.84 | CRBN (0.55) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL25133856 | 0.82 | IKZF2 (0.52) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| Trifluoroacetic Acid SCHEMBL30819813 | 0.81 | IKZF2 (0.57) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL27272299 | 0.81 | IKZF2 (0.52) | IKZF2CRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30798445 | 0.81 | IKZF2 (0.45) | IKZF2CRBNIKZF3DDB1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605387-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| WO-2024086759-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |