Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.57 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27136427 | 1.00 | EGFR (0.57) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL30979940 | 1.00 | EGFR (0.57) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL27136426 | 1.00 | EGFR (0.57) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL27138864 | 0.92 | EGFR (0.53) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL27138869 | 0.92 | EGFR (0.53) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL30822125 | 0.88 | EGFR (0.49) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL24714697 | 0.86 | EGFR (0.52) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL30979951 | 0.86 | EGFR (0.52) | EGFRERBB2KDRFGFR1FLT1 | |
| SCHEMBL30031665 | 0.86 | EGFR (0.52) | EGFRERBB2ABL1PDGFRBSRC | |
| SCHEMBL30031034 | 0.86 | EGFR (0.52) | EGFRERBB2ABL1PDGFRBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |