Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23551327 | 0.90 | DDB1 (0.52) | DDB1CRBNHTR4CNR1TLR9 | |
| SCHEMBL30822466 | 0.89 | DDB1 (0.53) | DDB1CRBNHTR7MCHR1TLR9 | |
| SCHEMBL30258186 | 0.88 | DDB1 (0.50) | DDB1CRBNMCHR1TLR9TLR8 | |
| SCHEMBL30915055 | 0.86 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL30822442 | 0.86 | DDB1 (0.50) | DDB1CRBNHTR4HTR7SLC6A3 | |
| SCHEMBL30822367 | 0.85 | DDB1 (0.51) | DDB1CRBNHTR4SLC6A3 | |
| SCHEMBL23538562 | 0.84 | DDB1 (0.55) | DDB1CRBNCNR1HRH3 | |
| SCHEMBL29946867 | 0.83 | DDB1 (0.54) | DDB1CRBNCNR1HRH3 | |
| SCHEMBL30703654 | 0.82 | DDB1 (0.48) | DDB1CRBNCNR1HRH3 | |
| SCHEMBL23539355 | 0.81 | DDB1 (0.49) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565585-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | Bristol-Myers Squibb Company (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030968-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2024-02-08 | — | — | WO | disclosed |