Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31333567 | 0.93 | DDB1 (0.52) | DDB1CRBNHDAC8 | |
| SCHEMBL24752797 | 0.90 | DDB1 (0.59) | DDB1CRBNHDAC8 | |
| SCHEMBL30258575 | 0.90 | DDB1 (0.57) | DDB1CRBNHDAC8 | |
| SCHEMBL30915148 | 0.88 | CRBN (0.51) | DDB1CRBNHDAC8 | |
| SCHEMBL29942842 | 0.87 | DDB1 (0.55) | DDB1CRBNHDAC8 | |
| SCHEMBL23301462 | 0.87 | DDB1 (0.55) | DDB1CRBNHDAC8 | |
| SCHEMBL30304273 | 0.87 | DDB1 (0.55) | DDB1CRBNHDAC8 | |
| SCHEMBL30919641 | 0.86 | DDB1 (0.58) | DDB1CRBNHDAC8 | |
| SCHEMBL30981388 | 0.85 | DDB1 (0.53) | DDB1CRBNHDAC8 | |
| SCHEMBL20595430 | 0.85 | DDB1 (0.74) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565585-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | Bristol-Myers Squibb Company (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030968-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2024-02-08 | — | — | WO | disclosed |