SCHEMBL30823366

SCHEMBL30823366

CC(C)(C)OC(=O)CN1CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)[C@@H](Cc2ccc(O)cc2)CN(CC(=O)OC(C)(C)C)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.38
PLA2G5 P39877 1/20 0.38
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
ADRA1D P25100 1/20 0.37
ADRA1A P35348 1/20 0.37
ADRA1B P35368 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
GRIN2C Q14957 1/20 0.37
GRIN3A Q8TCU5 1/20 0.37
ZDHHC9 Q9Y397 1/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.35
PPARG P37231 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9274528 1.00 PLA2G10 (0.38) PLA2G10PLA2G5GRIN2DGRIN3BADRA1D
SCHEMBL27145945 0.90 PLA2G10 (0.37) PLA2G10PLA2G5MAPTALDH1A1KDM4E
SCHEMBL5864550 0.90 PLA2G10 (0.37) PLA2G10PLA2G5PPARGCHRM2CHRM4
SCHEMBL23191925 0.90 PLA2G10 (0.37) PLA2G10PLA2G5PPARGCHRM2CHRM4
SCHEMBL27150526 0.90 PLA2G10 (0.37) PLA2G10PLA2G5MAPTALDH1A1KDM4E
SCHEMBL27145948 0.87 HRH3 (0.38) PLA2G10PLA2G5ALDH1A1SMN1; SMN2DPP4
SCHEMBL27148332 0.87 HRH3 (0.38) PLA2G10PLA2G5ALDH1A1SMN1; SMN2DPP4
SCHEMBL27269591 0.87 MEN1 (0.43) MAPTALDH1A1KDM4ESMN1; SMN2
SCHEMBL5864578 0.86 KCNJ1 (0.43) MAPTALDH1A1KDM4ESMN1; SMN2
SCHEMBL10375621 0.86 GRIN2B (0.44) PLA2G10PLA2G5GRIN2DGRIN3BADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577526-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2025-07-02 EP disclosed
WO-2024044549-A1 VHH ANTIBODY CONJUGATES Abdera Therapeutics Inc. (US) 2024-02-29 WO disclosed