Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 5/20 | 0.36 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL308236 | 1.00 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL4852665 | 0.98 | RNPEP (0.41) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL15111375 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL3898448 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL5150216 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL18886804 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL17473910 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL21221265 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 | |
| Racemethionine SCHEMBL20553497 | 0.96 | — | — | |
| Racemethionine SCHEMBL3898443 | 0.96 | RNPEP (0.42) | RNPEPANPEPENPEPMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114065-A1 | Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology | BIONEXUS, LTD. | 2008-05-15 | — | — | US | claimed |
| US-20040106591-A1 | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia | BIONEXUS, LTD. | 2004-06-03 | — | — | US | claimed |
| US-8093292-B2 | Conjugated fatty acid or alcohol, thiol-containing compound and bioavailable form of trivalent chromium; preventing metabolic dysregulation of adipocytes resulting from HIV-1 infection or chronic inflammation | BIONEXUS, LTD. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8017651-B2 | Conjugated fatty acid or alcohol, thiol-containing compound and bioavailable form of trivalent chromium | BIONEXUS, LTD. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20080114065-A1 | Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology | BIONEXUS, LTD. | 2008-05-15 | — | — | US | disclosed |
| US-20040106591-A1 | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia | BIONEXUS, LTD. | 2004-06-03 | — | — | US | disclosed |