Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568042 | 1.00 | S1PR3 (0.54) | S1PR3APEX1KMT2AMAPTMEN1 | |
| SCHEMBL6644972 | 0.94 | S1PR3 (0.53) | S1PR3APEX1KMT2AMAPTPOLB | |
| SCHEMBL20567823 | 0.92 | KMT2A (0.53) | S1PR3APEX1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6647212 | 0.91 | S1PR3 (0.53) | S1PR3APEX1KMT2AMAPTMEN1 | |
| SCHEMBL6330574 | 0.88 | KMT2A (0.58) | S1PR3APEX1KMT2AMAPTHTT | |
| SCHEMBL6639187 | 0.85 | KMT2A (0.54) | APEX1KMT2AMEN1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL6199458 | 0.84 | KMT2A (0.53) | APEX1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL6499867 | 0.84 | PDE5A (0.50) | KMT2AMAPTMEN1SMN1; SMN2POLB | |
| SCHEMBL20568064 | 0.82 | APEX1 (0.56) | S1PR3APEX1KMT2AMAPTMEN1 | |
| SCHEMBL6483636 | 0.82 | KMT2A (0.52) | S1PR3APEX1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063458-A | Novel dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-110621676-B | Dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof | 托帕杜制药公司 | 2024-02-09 | — | — | CN | disclosed |