Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.44 |
| ▸ | KDR | P35968 | 6/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086111 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL29514638 | 0.80 | ROCK1 (0.41) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL29089859 | 0.80 | GRM2 (0.37) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL21200262 | 0.80 | ROCK1 (0.41) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL21200175 | 0.80 | HTR2A (0.38) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL29841781 | 0.80 | HTR2A (0.38) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL21199788 | 0.80 | KDR (0.39) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL21200986 | 0.78 | KDR (0.38) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL21200672 | 0.78 | KDR (0.41) | PIK3CDPIK3CBPIK3CAKDRROCK1 | |
| SCHEMBL29867369 | 0.78 | KDR (0.38) | PIK3CDPIK3CBPIK3CAKDRROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858707-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |