SCHEMBL30825382

SCHEMBL30825382

CCNc1cc(-c2ccc(C#N)cc2-c2nncn2C)cc(N2Cc3c(cc(OC)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 17/20 0.57
▸ MAP4K1 Q92918 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27086256 1.00 CBLB (0.57) CBLBMAP4K1
SCHEMBL29920046 0.91 CBLB (0.57) CBLBMAP4K1
SCHEMBL27085962 0.91 CBLB (0.57) CBLBMAP4K1
SCHEMBL29920649 0.90 CBLB (0.60) CBLBMAP4K1
SCHEMBL27086136 0.90 CBLB (0.62) CBLBMAP4K1
SCHEMBL29920684 0.90 CBLB (0.62) CBLBMAP4K1
SCHEMBL27086112 0.90 CBLB (0.60) CBLBMAP4K1
SCHEMBL30825396 0.90 CBLB (0.62) CBLBMAP4K1
SCHEMBL27085877 0.90 CBLB (0.62) CBLBMAP4K1
SCHEMBL29920689 0.90 CBLB (0.63) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF SCHRÖDINGER, INC. 2025-08-21 — — US disclosed
CN-117858707-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263399-A1 CBL-B MODULATORS AND USES THEREOF CBLB, CBL, CBLC CBLB 1/4885MAP4K1 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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