Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29169534 | 1.00 | EGFR (0.70) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL3138953 | 0.98 | EGFR (0.72) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL28430681 | 0.98 | EGFR (0.72) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL3438262 | 0.98 | EGFR (0.72) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL30825572 | 0.95 | EGFR (0.74) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL1524509 | 0.95 | EGFR (0.74) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL28582218 | 0.95 | EGFR (0.74) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL1524510 | 0.95 | EGFR (0.74) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL11506980 | 0.85 | EGFR (0.55) | EGFRNPC1RAB9ACASP3SENP8 | |
| SCHEMBL11506984 | 0.85 | EGFR (0.55) | EGFRNPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117701516-A | Alkene reductase, enzyme preparation, nucleic acid, expression vector, preparation method and application | 河北工业大学 | 2024-03-15 | — | — | CN | disclosed |